CC0651 is an E2 enzyme inhibitor. It stabilizes the noncovalent CDC34A-donor ubiquitin complex .
| Product Name | CC0651 |
| Synonyms | |
| CAS Number | 1319207-44-7 |
| Related CAS | |
| Molecular Formula | C21H23Cl2NO5 |
| Molecular Weight | 440.32 |
| SMILES | COCC(=O)N[C@@H](CC1=CC=C(C=C1)C1=CC(Cl)=CC(Cl)=C1)[C@H](O)[C@@H](O)C(C)=O |
| Purity (HPLC) | >= 95% |
| Physical Appearance | White solid |
| Solubility | DMSO, DMF |
| Shipping Conditions | Room Temperature |
| Storage Conditions | Refrigerated |
| Shelf Life | 12 months after the date of delivery |
| Regulatory Statement | For Research Use Only |
References
Huang, H., Ceccarelli, D. F., Orlicky, S., St-Cyr, D. J., Ziemba, A., Garg, P., Plamondon, S., Auer, M., Sidhu, S., Marinier, A., Kleiger, G., Tyers, M., & Sicheri, F. (2014). E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin. Nature Chemical Biology, 10(2), 156–163. https://doi.org/10.1038/nchembio.1412
Documents
Datasheet COA MSDS
Citations
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