BODIPY FL VH032 is a high-affinity fluorescent probe for the von Hippel–Lindau (VHL) protein, with a Kd value of 3.01 nM. The BODIPY FL VH032 can be used in Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay, It can also be used for VHL ligand identification and characterization with high-throughput screening. As reported in the the following article: Development of BODIPY FL VH032 as a High-Affinity and Selective von Hippel–Lindau E3 Ligase Fluorescent Probe and Its Application in a Time-Resolved Fluorescence Resonance Energy-Transfer Assay, Wenwei Lin, Yongtao Li, Lei Yang, and Taosheng Chen, ACS Omega 2021, 6, 1, 680-695. 10.1021/acs.bioconjchem.0c00507
| Product Name | BODIPY FL VH032 |
| Synonyms | |
| CAS Number | n/a |
| Related CAS | |
| Molecular Formula | C46H62BF2N7O9S |
| Molecular Weight | 937.91 |
| SMILES | CC1=CC(C)=[N]2C1=CC1=CC=C(CCC(=O)NCCOCCOCCOCCOCC(=O)N[C@H](C(=O)N3C[C@H](O)C[C@H]3C(=O)NCC3=CC=C(C=C3)C3=C(C)N=CS3)C(C)(C)C)N1[B]2(F)F |
| Purity (HPLC) | 95% |
| Shipping Conditions | Room Temperature |
| Storage Conditions | Refrigerated |
| Regulatory Statemen: | For Research Use Only |