Cy5 Labeled Thalidomide is a fluorescent probe for cereblon E3 ligases. It binds with high affinity to DDB1-CRBN. Suitable for use in TR-FRET. Reference: Fischer, E. S., Böhm, K., Lydeard, J. R., Yang, H., Stadler, M. B., Cavadini, S., Nagel, J., Serluca, F., Acker, V., Lingaraju, G. M., Tichkule, R. B., Schebesta, M., Forrester, W. C., Schirle, M., Hassiepen, U., Ottl, J., Hild, M., Beckwith, R. E. J., Harper, J. W., … Thomä, N. H. (2014). Structure of the DDB1-CRBN E3 ubiquitin ligase in complex with thalidomide. Nature, 512(1), 49–53. https://doi.org/10.1038/nature13527
| Product Name | Cy5 Labeled Thalidomide |
| Synonyms | |
| CAS Number | N/A |
| Related CAS | |
| Molecular Formula | C51H59N6O7 |
| Molecular Weight | 868.067 |
| Purity (HPLC) | >= 95% |
| Shipping Conditions | Shipped on gel packs |
| Storage Conditions | Store at -20°C and protected from light |
| Regulatory Statement | For Research Use Only |