Cy5 Labeled Thalidomide

$190.00

T52461-1mg

Size: 1mg

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Cy5 Labeled Thalidomide is a fluorescent probe for cereblon E3 ligases. It binds with high affinity to DDB1-CRBN. Suitable for use in TR-FRET.

Product Name Cy5 Labeled Thalidomide
Synonyms
CAS Number N/A
Related CAS
Molecular Formula C51H59N6O7
Molecular Weight 868.067
Purity (HPLC) >= 95%
Physical Appearance Dark blue Solid
Optical Properties Abs/Em Maxima: 651/670 nm
Solubility DMSO
Shipping Conditions Shipped on gel packs
Storage Conditions Store at -20°C and protected from light
Shelf Life 12 months after the date of delivery
Regulatory Statement For Research Use Only


References

Fischer, E. S., Böhm, K., Lydeard, J. R., Yang, H., Stadler, M. B., Cavadini, S., Nagel, J., Serluca, F., Acker, V., Lingaraju, G. M., Tichkule, R. B., Schebesta, M., Forrester, W. C., Schirle, M., Hassiepen, U., Ottl, J., Hild, M., Beckwith, R. E. J., Harper, J. W., … Thomä, N. H. (2014). Structure of the DDB1-CRBN E3 ubiquitin ligase in complex with thalidomide. Nature, 512(1), 49–53. https://doi.org/10.1038/nature13527


Documents 

Datasheet         COA           MSDS


Citations

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