NDB-TM (HOCl probe)



Size: 1mg

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NBD-TM is a thiomorpholine-based fluorogenic probe for HOCl. NBD-TM proved to be the most rapid scavenger of HOCl when compared with boronate- and aminophenyl-based fluorogenic probes in a study for monitoring the chlorinating activity of Myeloperoxidase (MPO). Its high reactivity towards HOCl makes NBD-TM the probe of choice for HTS campaigns based on HOCl detection. Excitation maximum = 500 nm; emission maximum = 550 nm. Reference: Pierzchala, K., Pieta, M., Rola, M., Swierczynska, M., Artelska, A., Debowska, K., Podsiadly, R., Pieta, J., Zielonka, J., Sikora, A., Marcinek, A., & Michalski, R. (2022). Fluorescent probes for monitoring myeloperoxidase-derived hypochlorous acid: a comparative study. Scientific Reports, 12(1). https://doi.org/10.1038/s41598-022-13317-8

Product Name NDB-TM
CAS Number 871510-38-2
Related CAS
Molecular Formula C10H10N4O3S
Molecular Weight 266.28
Purity (HPLC) >= 95%
Shipping Conditions Shipped on gel packs
Storage Conditions Store at -20°C and protected from light
Regulatory Statement For Research Use Only