KI-MS2-008

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T55059-5mg

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KI-MS2-008 is a Max-binding modulator, attenuating Myc-driven transcription and stabilizing the Max homodimer.

Product Name KI-MS2-008
Synonyms
CAS Number n/a
Related CAS
Molecular Formula C32H28N2O4S
Molecular Weight 536.65
SMILES O=C1N(CCS(=O)(=O)C2=CC=CC=C2)CC2=CC=CC=C2[C@@H]2OC(=N[C@]12CC1=CC=CC=C1)C1=CC=CC=C1
Purity (HPLC) >= 95%
Physical Appearance White solid
Solubility DMSO, DMF
Shipping Conditions Room Temperature
Storage Conditions Refrigerated
Shelf Life 12 months after the date of delivery
Regulatory Statement For Research Use Only


References

Struntz, N. B., Chen, A., Deutzmann, A., Wilson, R. M., Stefan, E., Evans, H. L., Ramirez, M. A., Liang, T., Caballero, F., Wildschut, M. H. E., Neel, D. V., Freeman, D. B., Pop, M. S., McConkey, M., Muller, S., Curtin, B. H., Tseng, H., Frombach, K. R., Butty, V. L., Levine, S. S., Feau, C., Elmiligy, S., Hong, J. A., Lewis, T. A., Vetere, A., Clemons, P. A., Malstrom, S. E., Ebert, B. L., Lin, C. Y., Felsher, D. W.,Koehler, A. N., Stabilization of the Max Homodimer with a Small Molecule Attenuates Myc-Driven Transcription. Cell Chemical Biology 2019, 26, 711-723.e14.

 

Documents 

Datasheet         COA           MSDS

 

Citations

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