KI-MS2-008 is a Max-binding modulator, attenuating Myc-driven transcription and stabilizing the Max homodimer. Reference: Struntz, N. B., Chen, A., Deutzmann, A., Wilson, R. M., Stefan, E., Evans, H. L., Ramirez, M. A., Liang, T., Caballero, F., Wildschut, M. H. E., Neel, D. V., Freeman, D. B., Pop, M. S., McConkey, M., Muller, S., Curtin, B. H., Tseng, H., Frombach, K. R., Butty, V. L., Levine, S. S., Feau, C., Elmiligy, S., Hong, J. A., Lewis, T. A., Vetere, A., Clemons, P. A., Malstrom, S. E., Ebert, B. L., Lin, C. Y., Felsher, D. W.,Koehler, A. N., Stabilization of the Max Homodimer with a Small Molecule Attenuates Myc-Driven Transcription. Cell Chemical Biology 2019, 26, 711-723.e14.
| Product Name |
KI-MS2-008 |
| Synonyms |
|
| CAS Number |
n/a |
| Related CAS |
|
| Molecular Formula |
C32H28N2O4S |
| Molecular Weight |
536.65 |
| SMILES |
O=C1N(CCS(=O)(=O)C2=CC=CC=C2)CC2=CC=CC=C2[C@@H]2OC(=N[C@]12CC1=CC=CC=C1)C1=CC=CC=C1 |
| Purity (HPLC) |
98% |
| Shipping Conditions |
Room Temperature |
| Storage Conditions |
Refrigerated |
| Regulatory Statemen: |
For Research Use Only |
