QM-FN-SO3 (NIR amyloid-? live cell dye)

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T01215-1mg

Size: 1mg

5-10 business days

QM-FN-SO3 is small-molecule fluorescent probe designed for directly mapping of amyloid-?(A?) plaques in vivo. It exhibited extraordinary features of ultra-high S/N ratio, remarkable binding affinity with BBB penetrability, and high-performance near-infrared emission. The detection characteristics of QM-FN-SO3 greatly streamline and improve the protocols for A? analysis in living animals. QM-FN-SO3 serves as a promising alternative to commercial probes such as Thioflavin derivatives (ThT or ThS) for Alzheimer’s disease (AD) research. Excitation maximum = 500 nm; emission maximum = 670 nm.

Product Name QM-FN-SO3
Synonyms
CAS Number N/A
Related CAS
Molecular Formula C29H25N4NaO3S2
Molecular Weight 564.65
Purity (HPLC) >= 95%
Physical Appearance Dark red solid
Optical Properties Abs/Em Maxima: 500/670nm
Solubility DMSO, DMF
Shipping Conditions Shipped on gel packs
Storage Conditions Store at -20°C and protected from light
Shelf Life 12 months after the date of delivery
Regulatory Statement For Research Use Only


References

Yan, C., Dai, J., Yao, Y., Fu, W., Tian, H., Zhu, W. H., & Guo, Z. (2023). Preparation of near-infrared AIEgen-active fluorescent probes for mapping amyloid-? plaques in brain tissues and living mice. In Nature Protocols (Vol. 18, Issue 4, pp. 1316–1336). Springer Nature. https://doi.org/10.1038/s41596-022-00789-1

 

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