Rapamycin-LC-fluorecein

$1,000.00

T01195-1mg

Ships in 5-10 Business Days

Rapamycin-LC-fluorecein is fluorescein labled rapamycin.  It is  an excellent fluprescent probe to characterise FK506-binding proteins.  It has moderate affinity for the FK1 domains of FKBPS1 (177 nM) and FKBP2 (469 nM) and  is suitable for high-throughput screening .  See: Kozany, et al, ChemBioChem, 2009 10, 1402.

Product Name: Rapamycin-LC-fluorecein
Synonyms: C40-(Glycyl-6-hexanoic-(5(6)-Carboxamidofluorescien))-rapamycin
CAS Number: N/A
Molecular Formula: C80H103N3O21
Molecular Weight: 1442.7
SMILES: [H][C@@]1(C[C@@H](C)[C@]2([H])CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@H](C[C@]3([H])CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@@]3([H])C(=O)O2)OC)CC[C@@H](OC(=O)CNC(=O)CCCCCNC(=O)C2=CC=C(C(O)=O)C(=C2)C2C3C=CC(=O)C=C3OC3=CC(O)=CC=C23)[C@@H](C1)OC.[H][C@@]1(C[C@@H](C)[C@]2([H])CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@H](C[C@]3([H])CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@@]3([H])C(=O)O2)OC)CC[C@@H](OC(=O)CNC(=O)CCCCCNC(=O)C2=CC=C(C3C4C=CC(=O)C=C4OC4=CC(O)=CC=C34)C(=C2)C(O)=O)[C@@H](C1)OC
Purity (HPLC): ≥ 95%
Shipping Conditions: room temperature
Storage Conditions: Refrigerated
Regulatory Statement: For Research Use Only