Rapamycin-LC-fluorecein
$1,000.00
T01195-1mg
Rapamycin-LC-fluorecein is fluorescein labled rapamycin. It is an excellent fluprescent probe to characterise FK506-binding proteins. It has moderate affinity for the FK1 domains of FKBPS1 (177 nM) and FKBP2 (469 nM) and is suitable for high-throughput screening . See: Kozany, et al, ChemBioChem, 2009 10, 1402.
| Product Name: | Rapamycin-LC-fluorecein |
| Synonyms: | C40-(Glycyl-6-hexanoic-(5(6)-Carboxamidofluorescien))-rapamycin |
| CAS Number: | N/A |
| Molecular Formula: | C80H103N3O21 |
| Molecular Weight: | 1442.7 |
| SMILES: | [H][C@@]1(C[C@@H](C)[C@]2([H])CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@H](C[C@]3([H])CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@@]3([H])C(=O)O2)OC)CC[C@@H](OC(=O)CNC(=O)CCCCCNC(=O)C2=CC=C(C(O)=O)C(=C2)C2C3C=CC(=O)C=C3OC3=CC(O)=CC=C23)[C@@H](C1)OC.[H][C@@]1(C[C@@H](C)[C@]2([H])CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@H](C[C@]3([H])CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@@]3([H])C(=O)O2)OC)CC[C@@H](OC(=O)CNC(=O)CCCCCNC(=O)C2=CC=C(C3C4C=CC(=O)C=C4OC4=CC(O)=CC=C34)C(=C2)C(O)=O)[C@@H](C1)OC |
| Purity (HPLC): | ≥ 95% |
| Shipping Conditions: | room temperature |
| Storage Conditions: | Refrigerated |
| Regulatory Statement: | For Research Use Only |