RhGln is a small-molecule fluorescent probe for directly visualizing glutamine in live cells from brain tissues. It is a brightly fluorescent, stable, water soluble, and non-hydrolysable glutamine analog. RhGln has been demonstrate to provide direct visual evidence of an activity-dependent glutamine supply from astroglial networks to presynaptic structures under physiological conditions. RhGln has an absorption and emission maxima at 580 and 601 nm and a fluorescence emission quantum yield of 0.6. Reference: Cheung, G., Bataveljic, D., Visser, J., Kumar, N., Moulard, J., Dallérac, G., Mozheiko, D., Rollenhagen, A., Ezan, P., Mongin, C., Chever, O., Bemelmans, A. P., Lübke, J., Leray, I., & Rouach, N. (2022). Physiological synaptic activity and recognition memory require astroglial glutamine. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-28331-7
Product Name | RhGln |
Synonyms | |
CAS Number | N/A |
Related CAS | |
Molecular Formula | C38H43ClN4O5 |
Molecular Weight | 671.24 |
Purity (HPLC) | >= 95% |
Shipping Conditions | Shipped on gel packs |
Storage Conditions | Store at -20°C and protected from light |
Regulatory Statement | For Research Use Only |