Thalidomide-O-PEG5-C2-amine HCl

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T52129-100mg

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Proteolysis targeting chimera (PROTAC) building block. Contains an E3 ligase ligand with PEG linker and terminal amine. Ready for conjugation to a target protein ligand to form PROTACs containing Thalidomide as cereblon ligand.

Product Name: Thalidomide-O-PEG5-C2-amine HCl
Synonyms: 1H-?Isoindole-?1,?3(2H)?-?dione, 4-?[(17-?amino-?3,?6,?9,?12,?15-?pentaoxaheptadec-?1-?yl)?oxy]?-?2-?(2,?6-?dioxo-?3-?piperidinyl)?-?, hydrochloride (1:1)
CAS Number: 2341841-01-6
Molecular Formula: C25H36ClN3O10
Molecular Weight: 574.02
SMILES: Cl.NCCOCCOCCOCCOCCOCCOC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1
Purity (HPLC): 95%
Shipping Conditions: room temperature
Storage Conditions: Refrigerated
Regulatory Statement: For Research Use Only