SKU: T70004-100mg

MC-Val-Cit-PAB-PNP

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MC-Val-Cit-PABC-PNP is a cathepsin-cleavable ADC linker that connects antibodies to cytotoxic payloads through a Val–Cit peptide and PABC spacer, enabling protease-triggered payload release in lysosomal environments. It is commonly used in the synthesis of antibody–drug conjugates (ADCs) designed for targeted drug delivery within tumor microenvironments.

Product Name MC-Val-Cit-PAB-PNP
Synonyms MC-VC-PAB-PNP, Maleimidocaproyl-L-valine-L-citrulline-p-aminobenzyl alcohol p-nitrophenyl carbonate
CAS Number 159857-81-5
Related CAS
Molecular Formula C35H43N7O11
Molecular Weight 737.767
Purity (HPLC) >= 95%
Solubility DMSO, DMF
Shipping Conditions Shipped on gel packs
Storage Conditions Store at -20°C and protected from light
Shelf Life 12 months after the date of delivery
Regulatory Statement For Research Use Only


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Datasheet          MSDS

 

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