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OSu-Glu-VC-PAB-MMAE

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SuO-Glu-Val-Cit-PAB-MMAE (NHS-Glutarate-Val-Cit-PAB-MMAE) is a cleavable ADC linker–payload system consisting of a SuO-Glu-Val-Cit-PAB peptide linker and the microtubule-disrupting cytotoxic payload MMAE. This ADC building block is widely used in the synthesis of antibody-drug conjugates for cancer research, where the Val-Cit-PAB motif enables enzyme-cleavable release of MMAE inside target cells, supporting highly potent, targeted delivery in preclinical ADC discovery and optimization workflows.

Product Name OSu-Glu-VC-PAB-MMAE
Synonyms NHS-Glutarate-Val-Cit-PAB-MMAE
CAS Number 1895916-24-1
Related CAS
Molecular Formula C67H103N11O17
Molecular Weight 1334.621
Purity (HPLC) >= 95%
Solubility DMSO, DMF
Shipping Conditions Shipped on gel packs
Storage Conditions Store at -20°C and protected from light
Shelf Life 12 months after the date of delivery
Regulatory Statement For Research Use Only


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