CC-92480
CC-92480 - 5mg is backordered and will ship as soon as it is back in stock.
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CC-92480 promotes rapid and extensive degradation of Aiolos/Ikaros than s lenalidomide and pomalidomide.
| Product Name | CC-92480 |
| Synonyms | Mezigdomide |
| CAS Number | 2259648-80-9 |
| Related CAS | |
| Molecular Formula | C32H30FN5O4 |
| Molecular Weight | 567.621 |
| SMILES | [H][C@@]1(CCC(=O)NC1=O)N1CC2=C(C=CC=C2OCC2=CC=C(CN3CCN(CC3)C3=C(F)C=C(C=C3)C#N)C=C2)C1=O |
| Purity (HPLC) | >= 95% |
| Physical Appearance | White solid |
| Solubility | DMSO, DMF |
| Shipping Conditions | Room Temperature |
| Storage Conditions | Refrigerated |
| Shelf Life | 12 months after the date of delivery |
| Regulatory Statement | For Research Use Only |
References
Hansen, J. D., Correa, M., Nagy, M. A., Alexander, M., Plantevin, V., Grant, V., Whitefield, B., Huang, D., Kercher, T., Harris, R., Narla, R. K., Leisten, J., Tang, Y., Moghaddam, M., Ebinger, K., Piccotti, J., Havens, C. G., Cathers, B., Carmichael, J., Daniel, T., Vessey, R., Hamann, L. G., Leftheris, K., Mendy, D., Baculi, F., LeBrun, L. A., Khambatta, G.,Lopez-Girona, A., Discovery of CRBN E3 Ligase Modulator CC-92480 for the Treatment of Relapsed and Refractory Multiple Myeloma. Journal of Medicinal Chemistry 2020, 63, 6648-6676. https://doi.org/10.1021/acs.jmedchem.9b01928
Documents
Datasheet COA MSDS
Citations
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