Tenova Pharmaceuticals | SKU:
T55031-5mg
CFT7455
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CFT7455 is a cereblon E3 ligase modulator with high affinity (Kd of 0.9 nM). CFT7455 acts as a molecular glue. It is an orally active zinc finger transcription factors Ikaros (IKZF1), Aiolos (IKZF3) degrader.
| Product Name | CFT7455 |
| Synonyms | |
| CAS Number | 2504235-67-8 |
| Related CAS | |
| Molecular Formula | C28H27N3O4 |
| Molecular Weight | 469.541 |
| SMILES | [H][C@@]1(CCC(=O)NC1=O)N1C(=O)C2=C3C1=CC=C(CC1=CC=C(CN4CCOCC4)C=C1)C3=CC=C2 |
| Purity (HPLC) | >= 95% |
| Physical Appearance | White solid |
| Solubility | DMSO, DMF |
| Shipping Conditions | Room Temperature |
| Storage Conditions | Refrigerated |
| Shelf Life | 12 months after the date of delivery |
| Regulatory Statement | For Research Use Only |
References
Mullard, A., Targeted protein degraders crowd into the clinic. Nat Rev Drug Discov 2021, 20, 247-250.
Documents
Datasheet COA MSDS
Citations
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