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Tenova Pharmaceuticals  |  SKU: T01270-1mg

MaP555-DBCO (cell-permeable fluorogenic dye)

$290.00
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MaP555-DBCO is a fluorogenic probe for copper-free click chemistry applications. MaP555 is a small-molecule fluorogenic probe with excellent cell permeability. It is converted from 6-carboxytetramethylrhodamine (6-TAMRA) and has similar spectroscopic properties of 6-TAMRA. MaP555 has an acyl sulfamide structure which favors the spirolactam form, thus has excellent cell permeability. When the probe binds to its cellular targets, MaP555 mainly exists in the fluorescent zwitterion form. The good spectroscopic properties, high cell permeability and outstanding fluorogenicity of MaP555 make it very useful for wash-free, multicolour, live-cell nanoscopy. Excitation maximum = 558 nm; emission maximum = 578 nm.

Product Name MaP555-DBCO
Synonyms
CAS Number n/a
Related CAS
Molecular Formula C45H42N6O6S
Molecular Weight 794.93
Purity (HPLC) >= 95%
Physical Appearance
Optical Properties
Solubility
Shipping Conditions
Storage Conditions
Shelf Life 12 months after the date of delivery
Regulatory Statement For Research Use Only


References

Wang, L., Tran, M., D’Este, E., Roberti, J., Koch, B., Xue, L., & Johnsson, K. (2020). A general strategy to develop cell permeable and fluorogenic probes for multicolour nanoscopy. Nature Chemistry, 12(2), 165–172. https://doi.org/10.1038/s41557-019-0371-3

 

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