CC-885
CC-885 - 5mg is backordered and will ship as soon as it is back in stock.
Couldn't load pickup availability
CC-885 is a cereblon (CRBN) modulator with potent anti-tumour activity. CC-885 promotes degradation of GSPT1.
| Product Name | CC-885 |
| Synonyms | |
| CAS Number | 1010100-07-8 |
| Related CAS | |
| Molecular Formula | C22H21ClN4O4 |
| Molecular Weight | 440.88 |
| SMILES | CC1=CC=C(NC(=O)NCC2=CC3=C(C=C2)C(=O)N(C3)C2CCC(=O)NC2=O)C=C1Cl |
| Purity (HPLC) | >= 95% |
| Physical Appearance | White solid |
| Solubility | DMSO, DMF |
| Shipping Conditions | Room Temperature |
| Storage Conditions | Refrigerated |
| Shelf Life | 12 months after the date of delivery |
| Regulatory Statement | For Research Use Only |
References
Dong, G., Ding, Y., He, S.,Sheng, C., Molecular Glues for Targeted Protein Degradation: From Serendipity to Rational Discovery. Journal of Medicinal Chemistry 2021, 64, 10606-10620.Hansen, J. D., Correa, M., Alexander, M., Nagy, M., Huang, D., Sapienza, J., Lu, G., LeBrun, L. A., Cathers, B. E., Zhang, W., Tang, Y., Ammirante, M., Narla, R. K., Piccotti, J. R., Pourdehnad, M.,Lopez-Girona, A., CC-90009: A Cereblon E3 Ligase Modulating Drug That Promotes Selective Degradation of GSPT1 for the Treatment of Acute Myeloid Leukemia. Journal of Medicinal Chemistry 2021, 64, 1835-1843.
Documents
Datasheet COA MSDS
Citations
If you know of a paper that uses this product from Tenova Pharma, please let us know.
