Chlorsulfaquinoxaline
Chlorsulfaquinoxaline - 5mg is backordered and will ship as soon as it is back in stock.
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Chloroquinaxoline sulfonamide (CQS) are aryl sulfonamides with anticancer activity. Chloroquinaxoline sulfonamide (CQS) share the same mechanism of action as Indisulam. Chloroquinaxoline sulfonamide (CQS) promotes the recruitment of RBM39 (RNA binding motif protein 39) to the CUL4-DCAF15 E3 ubiquitin ligase for degadation.
| Product Name | Chlorsulfaquinoxaline |
| Synonyms | NSC 339004 |
| CAS Number | 97919-22-7 |
| Related CAS | |
| Molecular Formula | C14H11ClN4O2S |
| Molecular Weight | 334.78 |
| SMILES | NC1=CC=C(C=C1)S(=O)(=O)NC1=CN=C2C(Cl)=CC=CC2=N1 |
| Purity (HPLC) | >= 95% |
| Physical Appearance | White solid |
| Solubility | DMSO, DMF |
| Shipping Conditions | Room Temperature |
| Storage Conditions | Refrigerated |
| Shelf Life | 12 months after the date of delivery |
| Regulatory Statement | For Research Use Only |
References
Han, T., Goralski, M., Gaskill, N., Capota, E., Kim, J., Ting, T. C., Xie, Y., Williams, N. S.,Nijhawan, D., Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15. Science 2017, 356, eaal3755. DOI: 10.1126/science.aal3755
Documents
Datasheet COA MSDS
Citations
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