compound I-9
compound I-9 - 5mg is backordered and will ship as soon as it is back in stock.
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Compound I-9 induces degradation of GSPT1 through recruitment of CRBN ( EC50: 0.170 uM).
Product Name | compound I-9 |
Synonyms | |
CAS Number | n/a |
Related CAS | |
Molecular Formula | C27H29N5O3 |
Molecular Weight | 471.561 |
SMILES | CC(C)(C)C1=CC=C(C=C1)C(=O)N1CCC(=CC1)C1=CC2=NC=C(N2C=C1)N1CCC(=O)NC1=O |
Purity (HPLC) | >= 95% |
Physical Appearance | White solid |
Solubility | DMSO, DMF |
Shipping Conditions | Room Temperature |
Storage Conditions | Refrigerated |
Shelf Life | 12 months after the date of delivery |
Regulatory Statement | For Research Use Only |
References
Axford, J., Beckwith, R. E. J., BONAZZI, S., Buschmann, N., CERNIJENKO, A., DEWHURST, J., FAZAL, A., HESSE, M. J., HOLDER, L., HORNAK, V., Imase, H., Jain, R., Jin, X., Kerrigan, J. R., Lachal, J., Ma, F., Malik, H. A., MANNING, J. R., Mckay, D., MOREAU, R. J., NIMSGERN, P., O'Brien, G., Vulpetti, A., Yamada, K.,Zhao, J. Glue degraders and methods of use thereof. WO 2021/053555, 2021.
Documents
Datasheet COA MSDS
Citations
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