BODIPY labeled DCAF1 Binder
BODIPY labeled DCAF1 Binder - 200ug is backordered and will ship as soon as it is back in stock.
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BODIPY labeled DCAF1 Binder
BODIPY labeled DCAF1 Binder is a compound original used for DCAF1 TR-FRET assay in the Nat Commun 15, 275 (2024) paper studing DCAF1-based PROTACs. It is a high-affinity fluorescent probe for DCAF1, with a Kd value of 69 nM towards DCAF1 measured by fluorescence polarization.
| Product Name | BODIPY labeled DCAF1 Binder |
| Synonyms | |
| CAS Number | n/a |
| Related CAS | |
| Molecular Formula | C39H43BClF5N8O3 |
| Molecular Weight | 813.08 |
| Purity (HPLC) | >= 95% |
| Physical Appearance | Orange Solid |
| Optical Properties | Abs/Em Maxima: 503/509nm |
| Solubility | DMSO, DMF |
| Shipping Conditions | Shipped on gel packs |
| Storage Conditions | Store at -20°C and protected from light |
| Shelf Life | 12 months after the date of delivery |
| Regulatory Statement | For Research Use Only |
References
Schröder, M., Renatus, M., Liang, X. et al. DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance. Nat Commun 15, 275 (2024). https://doi.org/10.1038/s41467-023-44237-4
Documents
Citations
If you know of a paper that uses this product from Tenova Pharma, please let us know.
