DCAF1 Binder 13
DCAF1 Binder 13 - 1mg is backordered and will ship as soon as it is back in stock.
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DCAF1 Binder 13 is a potent and selective DCAF1 binder, which binds to DCAF1 with a Kd by SPR and IC50 by TR-FRET of <50 nM.
Product Name | DCAF1 Binder 13 |
Synonyms | |
CAS Number | n/a |
Related CAS | |
Molecular Formula | C28H35ClN6O |
Molecular Weight | 507.08 |
SMILES | CC(=O)N1CCN(CC1)C1=CC=C2C(NCCN)=NC(=NC2=C1)C1(CCCCC1)C1=CC=C(Cl)C=C1 |
Purity (HPLC) | >= 95% |
Physical Appearance | White solid |
Solubility | DMSO, DMF |
Shipping Conditions | Room Temperature |
Storage Conditions | Refrigerated |
Shelf Life | 12 months after the date of delivery |
Regulatory Statement | For Research Use Only |
References
Schröder, M., Renatus, M., Liang, X. et al. DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance. Nat Commun 15, 275 (2024). https://doi.org/10.1038/s41467-023-44237-4
Documents
Datasheet COA MSDS
Citations
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