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Tenova Pharmaceuticals  |  SKU: T55067-1mg

DCAF1 Binder 13

$390.00
Size

DCAF1 Binder 13 is a potent and selective DCAF1 binder, which binds to DCAF1 with a Kd by SPR and IC50 by TR-FRET of <50 nM.

Product Name DCAF1 Binder 13
Synonyms
CAS Number n/a
Related CAS
Molecular Formula C28H35ClN6O
Molecular Weight 507.08
SMILES CC(=O)N1CCN(CC1)C1=CC=C2C(NCCN)=NC(=NC2=C1)C1(CCCCC1)C1=CC=C(Cl)C=C1
Purity (HPLC) >= 95%
Physical Appearance White solid
Solubility DMSO, DMF
Shipping Conditions Room Temperature
Storage Conditions Refrigerated
Shelf Life 12 months after the date of delivery
Regulatory Statement For Research Use Only


References

Schröder, M., Renatus, M., Liang, X. et al. DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance. Nat Commun 15, 275 (2024). https://doi.org/10.1038/s41467-023-44237-4

 

Documents 

Datasheet         COA           MSDS

 

Citations

If you know of a paper that uses this product from Tenova Pharma, please let us know.

Tenova Pharmaceuticals

DCAF1 Binder 13

$390.00

DCAF1 Binder 13 is a potent and selective DCAF1 binder, which binds to DCAF1 with a Kd by SPR and IC50 by TR-FRET of <50 nM.

Product Name DCAF1 Binder 13
Synonyms
CAS Number n/a
Related CAS
Molecular Formula C28H35ClN6O
Molecular Weight 507.08
SMILES CC(=O)N1CCN(CC1)C1=CC=C2C(NCCN)=NC(=NC2=C1)C1(CCCCC1)C1=CC=C(Cl)C=C1
Purity (HPLC) >= 95%
Physical Appearance White solid
Solubility DMSO, DMF
Shipping Conditions Room Temperature
Storage Conditions Refrigerated
Shelf Life 12 months after the date of delivery
Regulatory Statement For Research Use Only


References

Schröder, M., Renatus, M., Liang, X. et al. DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance. Nat Commun 15, 275 (2024). https://doi.org/10.1038/s41467-023-44237-4

 

Documents 

Datasheet         COA           MSDS

 

Citations

If you know of a paper that uses this product from Tenova Pharma, please let us know.

Size

  • 1mg
View product