Order Online and Get 10% Off

Tenova Pharmaceuticals  |  SKU: T55024-10mg

CC-122

$190.00
Size

Avadomide (CC-122) is an orally active cereblon modulator. It promotes degradation of Aiolos and Ikaros proteins.

Product Name CC-122
Synonyms Avadomide
CAS Number 1015474-32-4
Related CAS
Molecular Formula C14H14N4O3
Molecular Weight 286.291
SMILES CC1=NC2=CC=CC(N)=C2C(=O)N1C1CCC(=O)NC1=O
Purity (HPLC) >= 95%
Physical Appearance White solid
Solubility DMSO, DMF
Shipping Conditions Room Temperature
Storage Conditions Refrigerated
Shelf Life 12 months after the date of delivery
Regulatory Statement For Research Use Only


References

Hagner, P. R., Man, H. W., Fontanillo, C., Wang, M., Couto, S., Breider, M., Bjorklund, C., Havens, C. G., Lu, G., Rychak, E., Raymon, H., Narla, R. K., Barnes, L., Khambatta, G., Chiu, H., Kosek, J., Kang, J., Amantangelo, M. D., Waldman, M., Lopez-Girona, A., Cai, T., Pourdehnad, M., Trotter, M., Daniel, T. O., Schafer, P. H., Klippel, A., Thakurta, A., Chopra, R.,Gand Dong, G., Ding, Y., He, S.,Sheng, C., Molecular Glues for Targeted Protein Degradation: From Serendipity to Rational Discovery. Journal of Medicinal Chemistry 2021, 64, 10606-10620.

 

Documents 

Datasheet         COA           MSDS

 

Citations

If you know of a paper that uses this product from Tenova Pharma, please let us know.