dCeMM3
dCeMM3 - 5mg is backordered and will ship as soon as it is back in stock.
Couldn't load pickup availability
dCeMM3 (Compound 3) is a glue degrader. dCeMM3 induces ubiquitination and degradation of cyclin K by prompting an interaction of CDK12-cyclin K with a CRL4B ligase complex.
| Product Name | dCeMM3 |
| Synonyms | |
| CAS Number | 311787-85-6 |
| Related CAS | |
| Molecular Formula | C14H11ClN4OS |
| Molecular Weight | 318.78 |
| SMILES | ClC1=CN=C(NC(=O)CSC2=NC3=CC=CC=C3N2)C=C1 |
| Purity (HPLC) | >= 95% |
| Physical Appearance | White solid |
| Solubility | DMSO, DMF |
| Shipping Conditions | Room Temperature |
| Storage Conditions | Refrigerated |
| Shelf Life | 12 months after the date of delivery |
| Regulatory Statement | For Research Use Only |
References
Mayor-Ruiz, C., Bauer, S., Brand, M., Kozicka, Z., Siklos, M., Imrichova, H., Kaltheuner, I. H., Hahn, E., Seiler, K., Koren, A., Petzold, G., Fellner, M., Bock, C., Müller, A. C., Zuber, J., Geyer, M., Thomä, N. H., Kubicek, S.,Winter, G. E., Rational discovery of molecular glue degraders via scalable chemical profiling. Nature Chemical Biology 2020, 16, 1199-1207. https://doi.org/10.1038/s41589-020-0594-x
Documents
Datasheet COA MSDS
Citations
If you know of a paper that uses this product from Tenova Pharma, please let us know.
