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Tenova Pharmaceuticals  |  SKU: T55042-5mg

E7820

$90.00
Size

E7820 is a molecular glue degrader like Indisulam. E7820 induce targeted degradation of the splicing factor RBM39 through recruitment of the E3 ubiquitin ligase CRL4DCAF15.

Product Name E7820
Synonyms
CAS Number 289483-69-8
Related CAS
Molecular Formula C17H12N4O2S
Molecular Weight 336.37
SMILES CC1=CC=C(NS(=O)(=O)C2=CC(=CC=C2)C#N)C2=C1C(=CN2)C#N
Purity (HPLC) >= 95%
Physical Appearance White solid
Solubility DMSO, DMF
Shipping Conditions Room Temperature
Storage Conditions Refrigerated
Shelf Life 12 months after the date of delivery
Regulatory Statement For Research Use Only


References

Faust, T. B., Yoon, H., Nowak, R. P., Donovan, K. A., Li, Z., Cai, Q., Eleuteri, N. A., Zhang, T., Gray, N. S.,Fischer, E. S., Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15. Nat Chem Biol 2020, 16, 7-14.

 

Documents 

Datasheet         COA           MSDS

 

Citations

If you know of a paper that uses this product from Tenova Pharma, please let us know.

Tenova Pharmaceuticals

E7820

$90.00

E7820 is a molecular glue degrader like Indisulam. E7820 induce targeted degradation of the splicing factor RBM39 through recruitment of the E3 ubiquitin ligase CRL4DCAF15.

Product Name E7820
Synonyms
CAS Number 289483-69-8
Related CAS
Molecular Formula C17H12N4O2S
Molecular Weight 336.37
SMILES CC1=CC=C(NS(=O)(=O)C2=CC(=CC=C2)C#N)C2=C1C(=CN2)C#N
Purity (HPLC) >= 95%
Physical Appearance White solid
Solubility DMSO, DMF
Shipping Conditions Room Temperature
Storage Conditions Refrigerated
Shelf Life 12 months after the date of delivery
Regulatory Statement For Research Use Only


References

Faust, T. B., Yoon, H., Nowak, R. P., Donovan, K. A., Li, Z., Cai, Q., Eleuteri, N. A., Zhang, T., Gray, N. S.,Fischer, E. S., Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15. Nat Chem Biol 2020, 16, 7-14.

 

Documents 

Datasheet         COA           MSDS

 

Citations

If you know of a paper that uses this product from Tenova Pharma, please let us know.

Size

  • 5mg
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