Tenova Pharmaceuticals  |  SKU: T55045-5mg

HQ005

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HQ005 is a Molecular glue degrader of cyclin K (DC50 = 41 nM).

Product Name HQ005
Synonyms
CAS Number 2750644-31-4
Related CAS
Molecular Formula C15H15N5O2S2
Molecular Weight 361.44
SMILES CC1=CN=C(NC(=O)CC2=CSC(NC3=NC(CO)=CC=C3)=N2)S1
Purity (HPLC) >= 95%
Physical Appearance White solid
Solubility DMSO, DMF
Shipping Conditions Room Temperature
Storage Conditions Refrigerated
Shelf Life 12 months after the date of delivery
Regulatory Statement For Research Use Only


References

Lv, L., Chen, P., Cao, L., Li, Y., Zeng, Z., Cui, Y., Wu, Q., Li, J., Wang, J.-H., Dong, M.-Q., Qi, X.,Han, T., Discovery of a molecular glue promoting CDK12-DDB1 interaction to trigger cyclin K degradation. eLife 2020, 9, e59994.

 

Documents 

Datasheet         COA           MSDS

 

Citations

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