SKU: T70001-1g

Val-Cit-PAB

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Val-Cit-PAB is a cleavable ADC linker featuring a Val–Cit dipeptide and a para-aminobenzyl (PAB) spacer. The Val–Cit sequence is selectively cleaved by cathepsin B in lysosomes, while the para-aminobenzyl (PAB) spacer supports self-immolative release of the attached drug.

Product Name Val-Cit-PAB
Synonyms VC-PAB-OH
CAS Number 159857-79-1
Related CAS
Molecular Formula C18H29N5O4
Molecular Weight 379.461
Purity (HPLC) >= 95%
Solubility DMSO, DMF
Shipping Conditions Shipped on gel packs
Storage Conditions Store at -20°C and protected from light
Shelf Life 12 months after the date of delivery
Regulatory Statement For Research Use Only


References

 

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Datasheet          MSDS

 

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