New products added! Learn more

Order Online and Get 10% Off

Tenova Pharmaceuticals  |  SKU: T55001-5mg

ZXH-1-161

$190.00
Size

ZXH-1-161 is a potent cereblon (CRBN) modulator with an IC50 value of 39 nM in MM1.S wild type cells. ZXH-1-161 has selective degradation activity towards GSPT1. ZXH-1-161 can be used for researching multiple myeloma.

Product Name ZXH-1-161
Synonyms
CAS Number 2407654-51-5
Related CAS
Molecular Formula C26H24N6O3
Molecular Weight 468.517
SMILES O=C1N(CC2=C1C=CC=C2NC1=NC(NC2=CC3=C(CCC3)C=C2)=NC=C1)C1CCC(=O)NC1=O
Purity (HPLC) >= 95%
Physical Appearance White solid
Solubility DMSO, DMF
Shipping Conditions Room Temperature
Storage Conditions Refrigerated
Shelf Life 12 months after the date of delivery
Regulatory Statement For Research Use Only


References

Powell, C. E., Du, G., Che, J., He, Z., Donovan, K. A., Yue, H., Wang, E. S., Nowak, R. P., Zhang, T., Fischer, E. S.,Gray, N. S., Selective Degradation of GSPT1 by Cereblon Modulators Identified via a Focused Combinatorial Library. ACS Chemical Biology 2020, 15, 2722-2730.

 

Documents 

Datasheet         COA           MSDS

 

Citations

If you know of a paper that uses this product from Tenova Pharma, please let us know.

Tenova Pharmaceuticals

ZXH-1-161

$190.00

ZXH-1-161 is a potent cereblon (CRBN) modulator with an IC50 value of 39 nM in MM1.S wild type cells. ZXH-1-161 has selective degradation activity towards GSPT1. ZXH-1-161 can be used for researching multiple myeloma.

Product Name ZXH-1-161
Synonyms
CAS Number 2407654-51-5
Related CAS
Molecular Formula C26H24N6O3
Molecular Weight 468.517
SMILES O=C1N(CC2=C1C=CC=C2NC1=NC(NC2=CC3=C(CCC3)C=C2)=NC=C1)C1CCC(=O)NC1=O
Purity (HPLC) >= 95%
Physical Appearance White solid
Solubility DMSO, DMF
Shipping Conditions Room Temperature
Storage Conditions Refrigerated
Shelf Life 12 months after the date of delivery
Regulatory Statement For Research Use Only


References

Powell, C. E., Du, G., Che, J., He, Z., Donovan, K. A., Yue, H., Wang, E. S., Nowak, R. P., Zhang, T., Fischer, E. S.,Gray, N. S., Selective Degradation of GSPT1 by Cereblon Modulators Identified via a Focused Combinatorial Library. ACS Chemical Biology 2020, 15, 2722-2730.

 

Documents 

Datasheet         COA           MSDS

 

Citations

If you know of a paper that uses this product from Tenova Pharma, please let us know.

Size

  • 5mg
View product