SNAP-tag is a self-labeling protein derived from human O6-alkylguanine-DNA-alkyltransferase. SNAP-tag reacts with covalently with O6-benzylguanine derivatives. SNAP-DOTA-tris(t-Bu) can be used to attach DOTA moiety to protein. DOTA has been used in many different diagnostic and therapeutic applications, such as MRI contrast agents, PET and SPECT imaging agents, and radiotherapeutic agents.
| Product Name | SNAP-DOTA-tris(t-Bu) |
| Synonyms | |
| CAS Number | n/a |
| Related CAS | |
| Molecular Formula | C41H64N10O8 |
| Molecular Weight | 825.025 |
| Purity (HPLC) | >= 95% |
| Physical Appearance | White Solid |
| Optical Properties | n/a |
| Solubility | DMSO, DMF |
| Shipping Conditions | Shipped on gel packs |
| Storage Conditions | Store at -20°C and protected from light |
| Shelf Life | 12 months after the date of delivery |
| Regulatory Statement | For Research Use Only |
References
Wilhelm, J., Kuhn, S., Tarnawski, M., Gotthard, G., Tunnermann, J., Tanzer, T., Karpenko, J., Mertes, N., Xue, L., Uhrig, U., Reinstein, J., Hiblot, J., & Johnsson, K. (2021). Kinetic and Structural Characterization of the Self-Labeling Protein Tags HaloTag7, SNAP-tag, and CLIP-tag. Biochemistry, 60(33), 2560–2575. https://doi.org/10.1021/acs.biochem.1c00266
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