Tram-bo is the fluorescent probe used in the discovery of Trametiglue. It contains an BODIPY moeity connected to Trametiglue scaffold.
| Product Name | Tram-bo |
| Synonyms | |
| CAS Number | n/a |
| Related CAS | |
| Molecular Formula | C47H46BF3IN9O7 |
| Molecular Weight | 1043.65 |
| Purity (HPLC) | >= 95% |
| Physical Appearance | Dark Solid |
| Optical Properties | Abs/Em Maxima: 576/589nm |
| Solubility | DMSO, DMF |
| Shipping Conditions | Shipped on gel packs |
| Storage Conditions | Store at -20°C and protected from light |
| Shelf Life | 12 months after the date of delivery |
| Regulatory Statement | For Research Use Only |
References
Khan, Z.M., Real, A.M., Marsiglia, W.M. et al. Structural basis for the action of the drug trametinib at KSR-bound MEK. Nature 588, 509–514 (2020). https://doi.org/10.1038/s41586-020-2760-4
Documents
Datasheet COA MSDS
Citations
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