CC-3060 is a Cereblon modulator and promotes ZBTB16 degradation by primarily engaging distinct structural degrons on CRBN-ZnF1 zinc finger domains.
| Product Name | CC-3060 |
| Synonyms | |
| CAS Number | 444288-86-2 |
| Related CAS | |
| Molecular Formula | C22H17N3O5 |
| Molecular Weight | 403.394 |
| SMILES | O=C1N(C2CCC(=O)NC2=O)C(=O)C2=C1C=CC=C2NCC1=CC2=CC=CC=C2O1 |
| Purity (HPLC) | >= 95% |
| Physical Appearance | White solid |
| Solubility | DMSO, DMF |
| Shipping Conditions | Room Temperature |
| Storage Conditions | Refrigerated |
| Shelf Life | 12 months after the date of delivery |
| Regulatory Statement | For Research Use Only |
References
Kozicka, Z.,Thomä, N. H., Haven't got a glue: Protein surface variation for the design of molecular glue degraders. Cell Chemical Biology 2021, 28, 1032-1047.
Documents
Datasheet COA MSDS
Citations
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