CA-PEG1-Biotin (Cell Permeable)
CA-PEG1-Biotin (Cell Permeable) - 100nmol is backordered and will ship as soon as it is back in stock.
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CA-PEG1-Biotin (Cell Permeable)
HaloTag is a self-labeling protein tag engineered from the haloalkane dehalogenase DhaA, originally isolated from Rhodococcus rhodochrous. Its active site binds chloroalkane (CA)substrates, forming an irreversible covalent bond. This stable linkage between the HaloTag protein and its ligand enables rapid and efficient isolation and purification of tagged proteins. CA-PEG1-Biotin is a cell-permeable Biotin-HaloTag ligand that enables rapid labeling of Halo-tagged proteins in live cells and their efficient isolation via streptavidin pull-down. It offers significant potential for studying fundamental cellular processes, such as genome duplication and chromatin maintenance.
| Product Name | CA-PEG1-Biotin (Cell Permeable) |
| Synonyms | Biotin-PEG1-Halo |
| CAS Number | |
| Related CAS | |
| Molecular Formula | C27H49ClN4O6S |
| Molecular Weight | 593.22 |
| Purity (HPLC) | >= 95% |
| Solubility | DMSO, DMF |
| Shipping Conditions | Shipped on gel packs |
| Storage Conditions | Store at -20°C and protected from light |
| Shelf Life | 12 months after the date of delivery |
| Regulatory Statement | For Research Use Only |
References
Yadav, A. K., Jadhav, A. S., Szczepanik, P., Fagherazzi, P., Kabelka, I., Vácha, R., Svenda, J., & Polasek-Sedlackova, H. (2024). Development of a cell-permeable Biotin-HaloTag ligand to explore functional differences between protein variants across cellular generations. https://doi.org/10.1101/2024.09.18.613519
Documents
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Citations
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