Medicinal Chemistry Services
At Tenova Pharma, we deliver high-quality solutions that meet the unique challenges of modern drug discovery. With a deep understanding of molecular interactions and therapeutic targets, our expert team collaborates closely with pharmaceutical and biotechnology partners to design, synthesize, and optimize novel compounds. Whether you need hit-to-lead follow-up library, lead optimization SAR study, or ADME-Tox profiling, trust Tenova Pharma to be your strategic partner in advancing your therapeutic pipeline.
Here are some examples of our work:
- Small Molecules
- PROTACs and Molecular Glues
- Antibody-Drug Conjugates (ADC)
- and more
Custom Synthesis Services
With years of expertise in synthetic chemistry, our team excels in designing and synthesizing complex organic molecules, intermediates, and building blocks for pharmaceuticals, biotech, and academic research.
Here are some examples of the products we work on:
- Final Target Synthesis
- Intermediate Synthesis
- Reference Compound Synthesis
- Stable-Isotope Labelled Compounds
- Bioconjugation Reagents
- Fluorescent Probes
- and more
Medicinal Chemistry Project
Our Client: a Pharmaceutical Company
Project: Kinase Inhibitors - Hit to Lead and Lead Optimization
Results:
- Developed hit compound modification strategies.
- Conducted extensive Structure Activity Relationship (SAR) studies.
- Synthesized over 200 compounds.
- Coordinated compound profiling through other vendors.
- Discovered potent, selective, and orally bioavailable lead compounds.
- Supported client on patent filings.
Academic Research Project
Our Client: an Academic Research Group
Project: Protein Tyrosine Phosphatases Inhibitors - Hit to Lead and Lead Optimization
Results:
- Worked on multiple projects.
- Developed synthetic methods with diverse chemistry.
- Synthesized over 300 compounds.
- Scaled up the lead compound at 100 gram scale.
- Supported client on publishing the results on leading scientific journals.
Custom Synthesis Project
Our Client: a Biotech Startup
Project: Synthesis of Chemiluminescence Compounds
Results:
- Other CROs failed on the synthesis.
- Re-designed the synthesis route.
- Fine-tuned the reaction conditions.
- Completed the 8-step synthesis successfully.
- Produced several hundred mg of the final products.