Small Molecule Medicinal Chemistry Project
Our Client: A Pharmaceutical Company
Project: Kinase Inhibitors - Hit to Lead and Lead Optimization
Results:
- Developed hit compound modification strategies
- Conducted extensive Structure Activity Relationship (SAR) studies
- Synthesized over 200 compounds
- Coordinated compound profiling through other vendors
- Discovered potent, selective, and orally bioavailable lead compounds
- Supported client on patent filings
Academic Research Project
Our Client: An Academic Research Group
Project: Protein Tyrosine Phosphatases Inhibitors - Hit to Lead and Lead Optimization
Results:
- Worked on multiple projects
- Developed synthetic methods with diverse chemistry
- Synthesized over 300 compounds
- Scaled up the lead compound at 100 gram scale
- Supported client on publishing the results on leading scientific journals