Rapamycin-LC-fluorescein is fluorescein labeled rapamycin. It is an excellent fluorescent probe to characterize FK506-binding proteins. It has moderate affinity for the FK1 domains of FKBPS1 (177 nM) and FKBP2 (469 nM) and is suitable for high-throughput screening . Reference: Kozany, C., März, A., Kress, C., & Hausch, F. (2009). Fluorescent probes to characterise FK506-binding proteins. ChemBioChem, 10(8), 1402–1410. https://doi.org/10.1002/cbic.200800806
| Product Name | Rapamycin-LC-fluorescein |
| Synonyms | C40-(Glycyl-6-hexanoic-(5(6)-Carboxamidofluorescien))-rapamycin |
| CAS Number | 1263034-82-7 |
| Related CAS | |
| Molecular Formula | C80H105N3O21 |
| Molecular Weight | 1444.72 |
| Purity (HPLC) | >= 95% |
| Shipping Conditions | Shipped on gel packs |
| Storage Conditions | Store at -20°C and protected from light |
| Regulatory Statement | For Research Use Only |