FPFT-2216
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FPFT-2216 is a molecular glue compound. It promotes degradeation of phosphodiesterase 6D (PDE6D), zinc finger transcription factors Ikaros (IKZF1), Aiolos (IKZF3), and casein kinase 1a (CK1a).
Product Name | FPFT-2216 |
Synonyms | |
CAS Number | 2367619-87-0 |
Related CAS | |
Molecular Formula | C12H12N4O3S |
Molecular Weight | 292.31 |
SMILES | COC1=CSC=C1C1=CN(N=N1)C1CCC(=O)NC1=O |
Purity (HPLC) | >= 95% |
Physical Appearance | White solid |
Solubility | DMSO, DMF |
Shipping Conditions | Room Temperature |
Storage Conditions | Refrigerated |
Shelf Life | 12 months after the date of delivery |
Regulatory Statement | For Research Use Only |
References
Teng, M., Lu, W., Donovan, K. A., Sun, J., Krupnick, N. M., Nowak, R. P., Li, Y.-D., Sperling, A. S., Zhang, T., Ebert, B. L., Fischer, E. S.,Gray, N. S., Development of PDE6D and CK1a Degraders through Chemical Derivatization of FPFT-2216. Journal of Medicinal Chemistry 2022, 65, 747-756.
Documents
Datasheet COA MSDS
Citations
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