CCT369260 is a potent BCL6 degrader.
| Product Name | CCT369260 |
| Synonyms | |
| CAS Number | 2253878-44-1 |
| Related CAS | |
| Molecular Formula | C25H33ClF2N6O |
| Molecular Weight | 507.03 |
| SMILES | C[C@H]1CN(C[C@@H](C)C1(F)F)C1=NC(NC2=CC3=C(C=C2)N(C)C(=O)N3CCC(C)(C)C)=C(Cl)C=N1 |
| Purity (HPLC) | >= 95% |
| Physical Appearance | White solid |
| Solubility | DMSO, DMF |
| Shipping Conditions | Room Temperature |
| Storage Conditions | Refrigerated |
| Shelf Life | 12 months after the date of delivery |
| Regulatory Statement | For Research Use Only |
References
Bellenie, B. R., Cheung, K.-M. J., Varela, A., Pierrat, O. A., Collie, G. W., Box, G. M., Bright, M. D., Gowan, S., Hayes, A., Rodrigues, M. J., Shetty, K. N., Carter, M., Davis, O. A., Henley, A. T., Innocenti, P., Johnson, L. D., Liu, M., de Klerk, S., Le Bihan, Y.-V., Lloyd, M. G., McAndrew, P. C., Shehu, E., Talbot, R., Woodward, H. L., Burke, R., Kirkin, V., van Montfort, R. L. M., Raynaud, F. I., Rossanese, O. W.,Hoelder, S., Achieving In Vivo Target Depletion through the Discovery and Optimization of Benzimidazolone BCL6 Degraders. Journal of Medicinal Chemistry 2020, 63, 4047-4068.
Documents
Datasheet COA MSDS
Citations
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