CA-Tz
CA-Tz - 100nmol is backordered and will ship as soon as it is back in stock.
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CA-Tz
HaloTag is a self-labeling protein tag engineered from the haloalkane dehalogenase DhaA, originally isolated from Rhodococcus rhodochrous. Its active site binds chloroalkane (CA)substrates, forming an irreversible covalent bond. This stable linkage between the HaloTag protein and its ligand enables rapid and efficient isolation and purification of tagged proteins. CA-Tetrazine is a HaloTag ligand containg a methayltetrazine group for click chemistry applications. Methyltetrazine is typically used in the inverse electron-demand Diels-Alder (iEDDA) reaction, a reaction where tetrazine compounds react with strained dienophiles, such as trans-cyclooctene (TCO) or norbornene derivatives. It is widely used for bioconjugation, fluorescent labeling, and live-cell imaging due to its high reactivity, bioorthogonality, and compatibility with biological systems.
| Product Name | CA-Tz |
| Synonyms | Methyltetrazine-Phenylacetyl-Halo, Tetrazine-CA |
| CAS Number | |
| Related CAS | |
| Molecular Formula | C21H30ClN5O3 |
| Molecular Weight | 435.95 |
| Purity (HPLC) | >= 95% |
| Solubility | DMSO, DMF |
| Shipping Conditions | Shipped on gel packs |
| Storage Conditions | Store at -20°C and protected from light |
| Shelf Life | 12 months after the date of delivery |
| Regulatory Statement | For Research Use Only |
References
Wilhelm, J., Kuhn, S., Tarnawski, M., Gotthard, G., Tunnermann, J., Tanzer, T., Karpenko, J., Mertes, N., Xue, L., Uhrig, U., Reinstein, J., Hiblot, J., & Johnsson, K. (2021). Kinetic and Structural Characterization of the Self-Labeling Protein Tags HaloTag7, SNAP-tag, and CLIP-tag. Biochemistry, 60(33), 2560–2575. https://doi.org/10.1021/acs.biochem.1c00261
Documents
Datasheet MSDS
Citations
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