Tenova Pharmaceuticals  |  SKU: T01295-100nmol

CA-PEG1-Biotin (Cell Permeable)

Regular price $290.00
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HaloTag is a self-labeling protein tag engineered from the haloalkane dehalogenase DhaA, originally isolated from Rhodococcus rhodochrous. Its active site binds chloroalkane (CA)substrates, forming an irreversible covalent bond. This stable linkage between the HaloTag protein and its ligand enables rapid and efficient isolation and purification of tagged proteins. CA-PEG1-Biotin is a cell-permeable Biotin-HaloTag ligand that enables rapid labeling of Halo-tagged proteins in live cells and their efficient isolation via streptavidin pull-down. It offers significant potential for studying fundamental cellular processes, such as genome duplication and chromatin maintenance.

Product Name CA-PEG1-Biotin (Cell Permeable)
Synonyms Ligand 5 (in the original publication), Biotin-PEG1-Halo
CAS Number
Related CAS
Molecular Formula C25H45ClN4O6S
Molecular Weight 565.2
Purity (HPLC) >= 95%
Solubility DMSO, DMF
Shipping Conditions Shipped on gel packs
Storage Conditions Store at -20°C and protected from light
Shelf Life 12 months after the date of delivery
Regulatory Statement For Research Use Only


References
Yadav, A. K., Jadhav, A. S., Szczepanik, P. M., Fagherazzi, P., Kabelka, I., Vácha, R., Svenda, J., & Polasek-Sedlackova, H. (2025). A biotin-HaloTag ligand enables efficient affinity capture of protein variants from live cells. Journal of Cell Biology, 224(8), e202410025. https://doi.org/10.1083/jcb.202410025

 

Documents 

Datasheet          MSDS

 

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