CP-Biotin
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SNAP-tag is a self-labeling protein derived from human O6-alkylguanine-DNA-alkyltransferase. At 20 kDa, SNAP-tag is smaller than HaloTag (33 kDa), potentially reducing interference with the tagged protein’s function. SNAP-tag reacts with covalently with benzylguanine (BG)or chloropyrimidine (CP) derivatives, forming a stable thioether bonds that ensures durability for long-term experiments or harsh conditions. SNAP-tag can be used alongside other tags like CLIP-tag for multicolor labeling. Chloropyrimidine (CP) derivatives generally exhibit better cell permeability compared to their benzylguanine (BG) derivatives. CP-Biotin is a SNAP-tag substrate containg biotin moiety. It forms a covalent bond with the SNAP-tag protein, ensuring stable labeling for long-term tracking. The biotinylated biomolecules can then be bound to avidin or streptavidin, enabling further purification and detection.
Product Name | CP-Biotin |
Synonyms | CP-Biotin, SNAP2-Biotin |
CAS Number | |
Related CAS | |
Molecular Formula | C22H27ClN6O3S |
Molecular Weight | 491.01 |
Purity (HPLC) | >= 95% |
Solubility | DMSO, DMF |
Shipping Conditions | Shipped on gel packs |
Storage Conditions | Store at -20°C and protected from light |
Shelf Life | 12 months after the date of delivery |
Regulatory Statement | For Research Use Only |
References
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