BODIPY FL VH032 is a high-affinity fluorescent probe for the von Hippel–Lindau (VHL) protein, with a Kd value of 3.01 nM. The BODIPY FL VH032 can be used in Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay, It can also be used for VHL ligand identification and characterization with high-throughput screening.
| Product Name | BODIPY FL VH032 |
| Synonyms | |
| CAS Number | 2770675-66-4 |
| Related CAS | |
| Molecular Formula | C46H62BF2N7O9S |
| Molecular Weight | 937.91 |
| Purity (HPLC) | >= 95% |
| Physical Appearance | Orange Solid |
| Optical Properties | Abs/Em Maxima: 502/511 nm |
| Solubility | DMSO |
| Shipping Conditions | Shipped on gel packs |
| Storage Conditions | Store at -20°C and protected from light |
| Shelf Life | 12 months after the date of delivery |
| Regulatory Statement | For Research Use Only |
References
Lin, W., Li, Y., Yang, L., & Chen, T. (2021). Development of BODIPY FL VH032 as a High-Affinity and Selective von Hippel-Lindau E3 Ligase Fluorescent Probe and Its Application in a Time-Resolved Fluorescence Resonance Energy-Transfer Assay. ACS Omega, 6(1), 680–695. https://doi.org/10.1021/acsomega.0c05221
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Citations
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