Compound 2ab
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Compound 2ab is a more potent E2 enzyme inhibitor than CC0651. It stabilizes the noncovalent CDC34A-donor ubiquitin complex .
| Product Name | Compound 2ab |
| Synonyms | |
| CAS Number | n/a |
| Related CAS | |
| Molecular Formula | C24H28Cl2N2O3 |
| Molecular Weight | 463.4 |
| SMILES | CCNC(=O)C1(CC2=CC=C(C=C2)C2=CC(Cl)=CC(Cl)=C2)CCN(CC1)C(=O)COC |
| Purity (HPLC) | >= 95% |
| Physical Appearance | White solid |
| Solubility | DMSO, DMF |
| Shipping Conditions | Room Temperature |
| Storage Conditions | Refrigerated |
| Shelf Life | 12 months after the date of delivery |
| Regulatory Statement | For Research Use Only |
References
St-Cyr, D., Ceccarelli, D. F., Orlicky, S., van der Sloot, A. M., Tang, X., Kelso, S., Moore, S., James, C., Posternak, G., Coulombe-Huntington, J., Bertomeu, T., Marinier, A., Sicheri, F., & Tyers, M. (2021). Identification and optimization of molecular glue compounds that inhibit a noncovalent E2 enzyme-ubiquitin complex. Science Advances, 7(44).
Documents
Datasheet COA MSDS
Citations
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