Compound 2ab

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T55022-5mg

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Compound 2ab is a more potent E2 enzyme inhibitor than CC0651. It stabilizes the noncovalent CDC34A-donor ubiquitin complex . Reference: St-Cyr, D., Ceccarelli, D. F., Orlicky, S., van der Sloot, A. M., Tang, X., Kelso, S., Moore, S., James, C., Posternak, G., Coulombe-Huntington, J., Bertomeu, T., Marinier, A., Sicheri, F., & Tyers, M. (2021). Identification and optimization of molecular glue compounds that inhibit a noncovalent E2 enzyme-ubiquitin complex. Science Advances, 7(44).
Product Name Compound 2ab
Synonyms
CAS Number n/a
Related CAS
Molecular Formula C24H28Cl2N2O3
Molecular Weight 463.4
SMILES CCNC(=O)C1(CC2=CC=C(C=C2)C2=CC(Cl)=CC(Cl)=C2)CCN(CC1)C(=O)COC
Purity (HPLC) 98%
Shipping Conditions Room Temperature
Storage Conditions Refrigerated
Regulatory Statemen: For Research Use Only