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Tenova Pharmaceuticals  |  SKU: T55008-5mg

compound I-13

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Compound I-13 induces degradation of Ikaros (IKZF1) through recruitment of CRBN( EC50: 0.006 uM).

Product Name compound I-13
Synonyms
CAS Number 2631059-94-2
Related CAS
Molecular Formula C12H11N3O3
Molecular Weight 245.238
SMILES CC1=CC2=C(C=C1)C(=NO2)N1CCC(=O)NC1=O
Purity (HPLC) >= 95%
Physical Appearance White solid
Solubility DMSO, DMF
Shipping Conditions Room Temperature
Storage Conditions Refrigerated
Shelf Life 12 months after the date of delivery
Regulatory Statement For Research Use Only


References

Axford, J., Beckwith, R. E. J., BONAZZI, S., Buschmann, N., CERNIJENKO, A., DEWHURST, J., FAZAL, A., HESSE, M. J., HOLDER, L., HORNAK, V., Imase, H., Jain, R., Jin, X., Kerrigan, J. R., Lachal, J., Ma, F., Malik, H. A., MANNING, J. R., Mckay, D., MOREAU, R. J., NIMSGERN, P., O'Brien, G., Vulpetti, A., Yamada, K.,Zhao, J. Glue degraders and methods of use thereof. WO 2021/053555, 2021.

 

Documents 

Datasheet         COA           MSDS

 

Citations

If you know of a paper that uses this product from Tenova Pharma, please let us know.

Tenova Pharmaceuticals

compound I-13

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Compound I-13 induces degradation of Ikaros (IKZF1) through recruitment of CRBN( EC50: 0.006 uM).

Product Name compound I-13
Synonyms
CAS Number 2631059-94-2
Related CAS
Molecular Formula C12H11N3O3
Molecular Weight 245.238
SMILES CC1=CC2=C(C=C1)C(=NO2)N1CCC(=O)NC1=O
Purity (HPLC) >= 95%
Physical Appearance White solid
Solubility DMSO, DMF
Shipping Conditions Room Temperature
Storage Conditions Refrigerated
Shelf Life 12 months after the date of delivery
Regulatory Statement For Research Use Only


References

Axford, J., Beckwith, R. E. J., BONAZZI, S., Buschmann, N., CERNIJENKO, A., DEWHURST, J., FAZAL, A., HESSE, M. J., HOLDER, L., HORNAK, V., Imase, H., Jain, R., Jin, X., Kerrigan, J. R., Lachal, J., Ma, F., Malik, H. A., MANNING, J. R., Mckay, D., MOREAU, R. J., NIMSGERN, P., O'Brien, G., Vulpetti, A., Yamada, K.,Zhao, J. Glue degraders and methods of use thereof. WO 2021/053555, 2021.

 

Documents 

Datasheet         COA           MSDS

 

Citations

If you know of a paper that uses this product from Tenova Pharma, please let us know.

Size

  • 5mg
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