Cy5 Labeled Thalidomide
Cy5 Labeled Thalidomide - 1mg is backordered and will ship as soon as it is back in stock.
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Cy5 Labeled Thalidomide
Cy5 Labeled Thalidomide is a fluorescent probe for cereblon E3 ligases. It binds with high affinity to DDB1-CRBN. Suitable for use in TR-FRET.
| Product Name | Cy5 Labeled Thalidomide |
| Synonyms | |
| CAS Number | N/A |
| Related CAS | |
| Molecular Formula | C51H59N6O7 |
| Molecular Weight | 868.067 |
| Purity (HPLC) | >= 95% |
| Physical Appearance | Dark blue Solid |
| Optical Properties | Abs/Em Maxima: 651/670 nm |
| Solubility | DMSO |
| Shipping Conditions | Shipped on gel packs |
| Storage Conditions | Store at -20°C and protected from light |
| Shelf Life | 12 months after the date of delivery |
| Regulatory Statement | For Research Use Only |
References
Fischer, E. S., Böhm, K., Lydeard, J. R., Yang, H., Stadler, M. B., Cavadini, S., Nagel, J., Serluca, F., Acker, V., Lingaraju, G. M., Tichkule, R. B., Schebesta, M., Forrester, W. C., Schirle, M., Hassiepen, U., Ottl, J., Hild, M., Beckwith, R. E. J., Harper, J. W., … Thomä, N. H. (2014). Structure of the DDB1-CRBN E3 ubiquitin ligase in complex with thalidomide. Nature, 512(1), 49–53. https://doi.org/10.1038/nature13527
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Citations
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