Tenova Pharmaceuticals  |  SKU: T55027-1mg

CC-647

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CC-647 is a Cereblon modulator, promoting ZBTB16 degradation by primarily engaging distinct structural degrons on CRBN-ZnF3 zinc finger domains.

Product Name CC-647
Synonyms
CAS Number 1061605-35-3
Related CAS
Molecular Formula C23H22N2O5
Molecular Weight 406.438
SMILES CC(C)(C)C1=CC=CC(OC2=CC=CC3=C2C(=O)N(C2CCC(=O)NC2=O)C3=O)=C1
Purity (HPLC) >= 95%
Physical Appearance White solid
Solubility DMSO, DMF
Shipping Conditions Room Temperature
Storage Conditions Refrigerated
Shelf Life 12 months after the date of delivery
Regulatory Statement For Research Use Only


References

Kozicka, Z.,Thomä, N. H., Haven't got a glue: Protein surface variation for the design of molecular glue degraders. Cell Chemical Biology 2021, 28, 1032-1047.


Documents 

Datasheet         COA           MSDS


Citations

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