CC-647 is a Cereblon modulator, promoting ZBTB16 degradation by primarily engaging distinct structural degrons on CRBN-ZnF3 zinc finger domains.
| Product Name | CC-647 |
| Synonyms | |
| CAS Number | 1061605-35-3 |
| Related CAS | |
| Molecular Formula | C23H22N2O5 |
| Molecular Weight | 406.438 |
| SMILES | CC(C)(C)C1=CC=CC(OC2=CC=CC3=C2C(=O)N(C2CCC(=O)NC2=O)C3=O)=C1 |
| Purity (HPLC) | >= 95% |
| Physical Appearance | White solid |
| Solubility | DMSO, DMF |
| Shipping Conditions | Room Temperature |
| Storage Conditions | Refrigerated |
| Shelf Life | 12 months after the date of delivery |
| Regulatory Statement | For Research Use Only |
References
Kozicka, Z.,Thomä, N. H., Haven't got a glue: Protein surface variation for the design of molecular glue degraders. Cell Chemical Biology 2021, 28, 1032-1047.
Documents
Datasheet COA MSDS
Citations
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