CC-99282
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Golcadomide (CC-99282) is a potent and orally active cereblon (CRBN) E3 ligase modulator. Golcadomide promotes potent and targeted degradation of Ikaros and Aiolos.
Product Name | CC-99282 |
Synonyms | |
CAS Number | 2379572-34-4 |
Related CAS | |
Molecular Formula | C28H30FN5O5 |
Molecular Weight | 535.576 |
SMILES | [H][C@@]1(CCC(=O)NC1=O)N1C(=O)C2=C(C1=O)C(NCC1=CC=C(CN3CC(C3)N3CCOCC3)C=C1F)=CC=C2 |
Purity (HPLC) | >= 95% |
Physical Appearance | White solid |
Solubility | DMSO, DMF |
Shipping Conditions | Room Temperature |
Storage Conditions | Refrigerated |
Shelf Life | 12 months after the date of delivery |
Regulatory Statement | For Research Use Only |
References
Mullard, A., Targeted protein degraders crowd into the clinic. Nat Rev Drug Discov 2021, 20, 247-250.
Documents
Datasheet COA MSDS
Citations
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