HQ005 is a Molecular glue degrader of cyclin K (DC50 = 41 nM).
| Product Name | HQ005 |
| Synonyms | |
| CAS Number | 2750644-31-4 |
| Related CAS | |
| Molecular Formula | C15H15N5O2S2 |
| Molecular Weight | 361.44 |
| SMILES | CC1=CN=C(NC(=O)CC2=CSC(NC3=NC(CO)=CC=C3)=N2)S1 |
| Purity (HPLC) | >= 95% |
| Physical Appearance | White solid |
| Solubility | DMSO, DMF |
| Shipping Conditions | Room Temperature |
| Storage Conditions | Refrigerated |
| Shelf Life | 12 months after the date of delivery |
| Regulatory Statement | For Research Use Only |
References
Lv, L., Chen, P., Cao, L., Li, Y., Zeng, Z., Cui, Y., Wu, Q., Li, J., Wang, J.-H., Dong, M.-Q., Qi, X.,Han, T., Discovery of a molecular glue promoting CDK12-DDB1 interaction to trigger cyclin K degradation. eLife 2020, 9, e59994.
Documents
Datasheet COA MSDS
Citations
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