Thalidomide-5-OH is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. It induces degradation of SALL4 (ZF2). Reference: Kozicka, Z., & Thoma, N. H. (2021). Haven’t got a glue: Protein surface variation for the design of molecular glue degraders. In Cell Chemical Biology (Vol. 28, Issue 7). https://doi.org/10.1016/j.chembiol.2021.04.009
| Product Name |
5-Hydroxythalidomide |
| Synonyms |
|
| CAS Number |
64567-60-8 |
| Related CAS |
|
| Molecular Formula |
C13H10N2O5 |
| Molecular Weight |
274.232 |
| SMILES |
OC1=CC2=C(C=C1)C(=O)N(C1CCC(=O)NC1=O)C2=O |
| Purity (HPLC) |
98% |
| Shipping Conditions |
Room Temperature |
| Storage Conditions |
Refrigerated |
| Regulatory Statemen: |
For Research Use Only |
