5-Hydroxythalidomide

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T55063-100mg

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Thalidomide-5-OH is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. It induces degradation of SALL4 (ZF2). Reference: Kozicka, Z., & Thoma, N. H. (2021). Haven’t got a glue: Protein surface variation for the design of molecular glue degraders. In Cell Chemical Biology (Vol. 28, Issue 7). https://doi.org/10.1016/j.chembiol.2021.04.009
Product Name 5-Hydroxythalidomide
Synonyms
CAS Number 64567-60-8
Related CAS
Molecular Formula C13H10N2O5
Molecular Weight 274.232
SMILES OC1=CC2=C(C=C1)C(=O)N(C1CCC(=O)NC1=O)C2=O
Purity (HPLC) 98%
Shipping Conditions Room Temperature
Storage Conditions Refrigerated
Regulatory Statemen: For Research Use Only