BODIPY FL Thalidomide

$290.00

SKU: T52674-1mg

In Stock

BODIPY FL Thalidomide is a high-affinity fluorescent probe for the human Cereblon protein, with a Kd value of 3.6 nM.  The BODIPY FL thalidomide-mediated Cereblon Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay,  is highly sensitive, selective, and stable.  As reported in the the follwoing article: Wenwei Lin, Yongtao Li, Jaeki Min, Jiuyu Liu, Lei Yang, Richard E. Lee, and Taosheng Chen, Development of BODIPY FL Thalidomide As a High-Affinity Fluorescent Probe for Cereblon in a Time-Resolved Fluorescence Resonance Energy Transfer Assay
Bioconjugate Chemistry 2020 31 (11), 2564-2575. DOI: 10.1021/acs.bioconjchem.0c00507

Product Name: BODIPY FL Thalidomide
Synonyms:
CAS Number:
Molecular Formula:
C37H43BF2N6O7
Molecular Weight: 732.59
SMILES:
CC1=CC(C)=[N]2C1=CC1=CC=C(CCC(=O)NCCCCCCCCNC(=O)COC3=C4C(=O)N(C5CCC(=O)NC5=O)C(=O)C4=CC=C3)N1[B]2(F)F
Purity (HPLC): 95%
Shipping Conditions: room temperature
Storage Conditions: Refrigerated
Regulatory Statement: For Research Use Only