BODIPY FL Thalidomide is a high-affinity fluorescent probe for the human Cereblon protein, with a Kd value of 3.6 nM. The BODIPY FL thalidomide-mediated Cereblon Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay, is highly sensitive, selective, and stable. Reference: Lin, W., Li, Y., Min, J., Liu, J., Yang, L., Lee, R. E., & Chen, T. (2020). Development of BODIPY FL Thalidomide As a High-Affinity Fluorescent Probe for Cereblon in a Time-Resolved Fluorescence Resonance Energy Transfer Assay. Bioconjugate Chemistry, 31(11), 2564–2575. https://doi.org/10.1021/acs.bioconjchem.0c00507
| Product Name | BODIPY FL Thalidomide |
| Synonyms | |
| CAS Number | 2740620-18-0 |
| Related CAS | |
| Molecular Formula | C37H43BF2N6O7 |
| Molecular Weight | 732.59 |
| Purity (HPLC) | >= 95% |
| Shipping Conditions | Shipped on gel packs |
| Storage Conditions | Store at -20°C and protected from light |
| Regulatory Statement | For Research Use Only |